Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep814 | Pituitary and Neuroendocrinology | ECE2022

Exploring a new entity of monotherapy pembrolizumab-associated hypophysitis

Balti Eric , Verhaeghe Sarah , Kruse Vibeke , Roels Stijn , Coremans Peter

Background: There are increasing number of reports on immune checkpoint inhibitors induced adverse events including hypophysitis. Hypophysitis tends to occur more with CytotoxicT-lymphocyte-associated protein 4 inhibitors (12-15% of cases) which is a different entity compared to those associated to anti-program death 1 (anti-PD1) inhibitors.Aim: We describe a case of pembrolizumab-associated hypophysitis and conduct a discussion based on a systematic rev...